The role of activated stromal fibroblasts in regulation of progression of human hematopoietic malignancies
Project leader: Jozef Bizik
Project duration: 2006 - 2008
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Analysis of alterations in genes responsible for onset of hereditary forms of breast and ovary cancer
Project leader: Miroslav Tomka
Project duration: 2006 - 2008
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Gene therapy for cancer with retrovirus vectors. Testing of vectors with tumor necrosis factor and vectors with siRNA expression cassette.
Project leader: Kristína Hlubinová
Project duration: 2006 - 2008
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Contribution of homologous recombination and non-homologous end-joining to DNA double-strand break repair after oxidative stress in the budding yeast Saccharomyces cerevisiae
Project leader: Miroslav Chovanec
Project duration: 2006 - 2008
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The role of genotoxic and epigenetic mechanisms in tissue and organ specificity of chemical carcinogens; mammalian cells cultivated in vitro as a model system
Project leader: Alena Gábelová
Project duration: 2006 - 2008
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The role of nuclear factor-1 in growth regulated expression of the human ANT2 gene.
Project leader: Peter Baráth
Project duration: 2006 - 2008
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Cloning, expression and purification of human homologs XPB and XPD from hyperthermophilic Archaeon, Pyrococcus abyssi
Project leader: Milan Škorvaga
Project duration: 2006 - 2008
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Further in vivo characterization of the mutant and polymorphic DNA ligase IV proteins found in LIG4 patients
Project leader: Miroslav Chovanec
Project duration: 2006 - 2009
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Epithelial-mesenchymal transition in the model of breast carcinoma stem cells in vitro.
Project leader: Ján Sedlák
Project duration: 2006 - 2009
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A role of the ERCC3 DNA helicase in DNA repair and apoptosis
Project leader: Miroslav Piršel
Project duration: 2007 - 2009
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Yeast K.lactis as a tool for study the mechanism of Bax induced cytotoxicity: A role for actin-binding proteins and lactate metabolism.
Project leader: Ľudmila Šabová
Project duration: 2007 - 2009
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The study of normal and leukemia hematopoietic populations as a basis for differentiation leukemic and regenerating cells
Project leader: Oľga Babušíková
Project duration: 2007 - 2009
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Chemotherapy, multidrug resistance (MDR), its modulation and relationship of these events to programmed cell death in human tumor cells
Project leader: Jozef Duraj
Project duration: 2007 - 2009
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Human adipose tissue-derived mesenchymal stem cell interaction with cancer cells
Project leader: Lucia Kučerová
Project duration: 2007 - 2009
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Cytogenetic monitoring of the reponses of the cells of the patients with carcinoma of the cervix uteri to the radiation from the view of prediction of the radiotherapy succes
Project leader: Ivan Chalupa
Project duration: 2007 - 2009
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DNA methylation in hereditary and sporadic colorectal carcinomas with mismatch repair defect
Project leader: Ivana Fridrichová
Project duration: 2007 - 2009
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Effect of natural compounds isothiocyanates (ITCs) on cellular mechanisms and markers associated with aggressive phenotype and treatment responsiveness in breast and ovarian cancer.
Project leader: Ľubica Hunáková
Project duration: 2008 - 2010
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The role of genetic, epigenetic and phenotypic markers of the MDR1 gene and protein for the prognosis and treatment of the acute myeloid leukemia.
Project leader: Zdena Bartošová
Project duration: 2008 - 2010
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Biological effect of novel mutation of the RET gene associated with multiple endocrine neoplasia type 2.
Project leader: Martina Poturnajová
Project duration: 2008 - 2010
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Study of genetic and non-genetic factors participated in induction of familial adenomatous polyposis (FAP) and sporadic form of colon cancer.
Project leader: Vladimír Zajac
Project duration: 2008 - 2010
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Molecular markers for prediction of individual radiosensitivity in cancer therapy
Project leader: Eva Marková
Project duration: 2008 - 2010
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Soluble non-classical HLA class I antigens
Project leader: Katarína Poláková
Project duration: 2008 - 2010
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The role and the contribution of Escherichia coli and Schizosaccharomyces pombe alkyltransferase homologues (ATL| in the repair of DNA alkylation damage in yeast Saccharomyces cerevisiae
Project leader: Karol Kleibl
Project duration: 2008 - 2010
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Integration of nuclear factor-1 (NF1) into existing signaling pathways leading to growth arrest
Project leader: Katarína Luciaková
Project duration: 2008 - 2010
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Human stem cells in cancer gene therapy
Project leader: Čestmír Altaner
Project duration: 2008 - 2012
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