Effect of natural compounds isothiocyanates (ITCs) on cellular mechanisms and markers associated with aggressive phenotype and treatment responsiveness in breast and ovarian cancer.
Project leader: Ľubica Hunáková
Project duration: 2008 - 2010
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The role of genetic, epigenetic and phenotypic markers of the MDR1 gene and protein for the prognosis and treatment of the acute myeloid leukemia.
Project leader: Zdena Bartošová
Project duration: 2008 - 2010
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Biological effect of novel mutation of the RET gene associated with multiple endocrine neoplasia type 2.
Project leader: Martina Poturnajová
Project duration: 2008 - 2010
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Study of genetic and non-genetic factors participated in induction of familial adenomatous polyposis (FAP) and sporadic form of colon cancer.
Project leader: Vladimír Zajac
Project duration: 2008 - 2010
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Molecular markers for prediction of individual radiosensitivity in cancer therapy
Project leader: Eva Marková
Project duration: 2008 - 2010
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Soluble non-classical HLA class I antigens
Project leader: Katarína Poláková
Project duration: 2008 - 2010
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The role and the contribution of Escherichia coli and Schizosaccharomyces pombe alkyltransferase homologues (ATL| in the repair of DNA alkylation damage in yeast Saccharomyces cerevisiae
Project leader: Karol Kleibl
Project duration: 2008 - 2010
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Integration of nuclear factor-1 (NF1) into existing signaling pathways leading to growth arrest
Project leader: Katarína Luciaková
Project duration: 2008 - 2010
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Molecular mechanisms of DNA interstrand cross-link repair in Saccharomyces cerevisiae
Project leader: Miroslav Chovanec
Project duration: 2009 - 2011
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Identification of alternative protein partners of tumor suppressors from INK4 family
Project leader: Ján Markus
Project duration: 2009 - 2011
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Study of essential oils and their components from the point of view of the protective action in the initiation step of carcinogenesis; experimental systems in vitro and ex vivo
Project leader: Eva Horváthová
Project duration: 2009 - 2011
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Gene-cell therapy of cancer using a self-inactivating - retroviral vectors inducibly expressing tumour necrosis factor alpha in human mesenchymal stem cells.
Project leader: Silvia Tyčiaková
Project duration: 2009 - 2011
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Molecular mechanisms of DNA interstrand cross-link repair in Saccharomyces cerevisiae
Project leader: Miroslav Chovanec
Project duration: 2009 - 2011
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Human stem cells in cancer gene therapy
Project leader: Čestmír Altaner
Project duration: 2008 - 2012
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Activation of stromal cells from human leukemic bone marrow by nemosis - a novel biological tool in diagnosis of leukemia and therapy monitoring
Project leader: Jozef Bizik
Project duration: 2009 - 2012
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Molecular mechanisms of magnetite nanoparticle interactions due to internalisation and accumulation in cells in vitro
Project leader: Alena Gábelová
Project duration: 2009 - 2012
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Study of interactions between between tumour cells and mesenchymal stem cells carrying suicide genes
Project leader: Miroslava Matúšková
Project duration: 2010 - 2012
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T-cell lineage differentiation antigens and T-cell maturation sequence in the management of T-acute leukemia patients.
Project leader: Ján Kusenda
Project duration: 2010 - 2012
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Cisplatin resistance in human ovarian cancer cells and its modulation by signaling pathway- and nuclear transcription factor NF kappa-B inhibition
Project leader: Jozef Duraj
Project duration: 2010 - 2012
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Epigenetic inactivation of selected genes for growth, invasivity and metastasis regulation in breast cancers diagnosis
Project leader: Ivana Fridrichová
Project duration: 2010 - 2012
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PARP-1 inhibitors:genetically specific compounds for therapy of BRCA1/2 defected cancers
Project leader: Ivana Fridrichová
Project duration: 2010 - 2012
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The role of nucleotide excision repair in DNA damage response
Project leader: Miroslav Piršel
Project duration: 2010 - 2013
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