---------------------------------------------------------------------------
CONFERENCE PROGRAM - pdf file
Rebeka Tomasin, Laboratory of Nutrition and Cancer, Institute of Biology, State University of Campinas, UNICAMP, Campinas, Brazil: Aloe vera and honey reduce tumour growth by decreasing its cell proliferative capacity in tumour-bearing rats.
Katarzyna Lubelska, National Medicines Institute, Warsaw, Poland: Sulforaphane and alyssin as chemopreventive agents.
Luba Hunakova, Cancer Research Institute SAS, Bratislava, Slovakia: Modulation of markers associated with aggressive phenotype in MDA-MB-231 breast carcinoma cells by sulforaphane.
Peter Kutschy, Institute of Chemical Sciences, Faculty of Science, UPJS, Kosice, Slovakia: 1-methoxyindole phytoalexins: synthesis and anticancer activity.
Monia Lenzi, Department of Pharmacology, University of Bologna, Italy: Combination of doxorubicin and sulforaphane for reversing doxorubicin-resistant phenotype in mice fibroblasts with p53(Ser220) mutation.
Magdalena Milczarek, National Medicines Institute, Warsaw, Poland: Analysis of interaction of isothiocyanates with 5-fluorouracil in chinese hamster lung fibroblast cell line.
Petr Benes, Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic: Wedelolactone reduces growth and induces differentiation and apoptosis of breast cancer cells.
Alexandra Hudecova , Comet assay: a useful method in studies of Gentiana asclepiadea and Papaver rhoeas methanolic flower extracts.
Anna Smiechowska , The impact of cultivations on phytocomlex composition and chemopreventive properties of white cabbage.
TUESDAY 13 OCT 2009
WEDNESDAY 14 OCT 2009
THURSDAY 15 OCT 2009
CONFERENCE PROGRAM - pdf file
DAY1
Opening Ceremony
16:00 Opening remarks & The ITC research in Slovakia
- Coevals of prof. Drobnica, The history of ITC research in Slovakia: the fifties of the last century
- Jan Sedlak, director of Cancer Research Institute SAS, The last 10 years of ITC research in Slovakia
- Jana Jakubikova, Dana-Farber Cancer Institute, Boston, USA, Cancer Research Institute SAS, Bratislava, Slovakia: Isothiocyanates exert anti-myeloma activity and enhance therapeutic cytotoxicity.
Intervention Studies and Functional Food
18:00 Section V.
- Richard Mithen, IFR Norwich, UK: Human intervention studies with isothiocyanate rich food products, role of human genetic polymorphisms and mechanisms of action in vivo.
- Dana Cholujova, Cancer Research Institute SAS, Bratislava, Slovakia: BioBran modulates the innate immune system functions: multiple myeloma patients’ study.
- Emil Tomasik, INFREDPharm, Slovakia: The perspective use of the preparation Mellozan in oncology.
- Kean Ashurst, Sulforaphane ( ITC’s) Applications for Improved Health - Yesterday! – Today! – Tomorrow!
Welcome Party
20:00 Smolenice Castle
DAY1
Opening Ceremony
16:00 Opening remarks & The ITC research in Slovakia- Coevals of prof. Drobnica, The history of ITC research in Slovakia: the fifties of the last century
- Jan Sedlak, director of Cancer Research Institute SAS, The last 10 years of ITC research in Slovakia
- Jana Jakubikova, Dana-Farber Cancer Institute, Boston, USA, Cancer Research Institute SAS, Bratislava, Slovakia: Isothiocyanates exert anti-myeloma activity and enhance therapeutic cytotoxicity.
Intervention Studies and Functional Food
18:00 Section V.- Richard Mithen, IFR Norwich, UK: Human intervention studies with isothiocyanate rich food products, role of human genetic polymorphisms and mechanisms of action in vivo.
- Dana Cholujova, Cancer Research Institute SAS, Bratislava, Slovakia: BioBran modulates the innate immune system functions: multiple myeloma patients’ study.
- Emil Tomasik, INFREDPharm, Slovakia: The perspective use of the preparation Mellozan in oncology.
- Kean Ashurst, Sulforaphane ( ITC’s) Applications for Improved Health - Yesterday! – Today! – Tomorrow!
Welcome Party
20:00 Smolenice Castle
DAY2
Chemoprevention, chemoprotection
9:00 Section I.- Clarissa Gerhauser, German Cancer Research Center, Heidelberg, Germany: Prostate cancer preventive potential of broccoli.
- Yongping Bao, University of East Anglia, Norwich, UK : Novel targets of isothiocyanates in cancer prevention.
- Katarzyna Skupinska, National Medicines Institute, Warsaw, Poland: Isothiocyanates as chemopreventive agents against polycyclic aromatic hydrocarbons.
- Monika Kassayova, Melatonin in the prevention of experimental mammary carcinogenesis.
- Rudolf Štětina, The influence of antioxidants (ellagic acid, epigallocatechin gallate) on the removal of DNA damage induced with different chemical mutagens.
Biomarkers and Epidemiology
11:15 Section III.- Andrew Collins, Department of Nutrition, University of Oslo,Norway: Non-antioxidant effects of antioxidants.
- Jian-Min Yuan, University of Minnesota, MN, USA: Isothiocyanates and Cancer Prevention – are we ready to move from observational studies to large clinical trials?
- Kristin Moy, University of Minnesota, MN, USA: Urinary ITC and GI tract neoplasms: colorectal and stomach cancer.
- Katarina Volkovova, Oxidative damage and antioxidant protection in relation to ageing.
Plant Biochemistry/Biotechnology and Organic Chemistry
14:00 Section IV.- Barbara Halkier, Faculty of Life Sciences, University of Copenhagen, Frederiksberg, Denmark: Engineering of glucosinolates in non-cruciferous plants.
- Eva Cellarova, Faculty of Science, UPJS, Kosice, Slovakia: Biotechnological alternative in production of bioactive substances in the genus Hypericum.
- Jan Imrich, Institute of Chemistry, Faculty of Science, UPJS, Kosice, Slovakia: Synthesis and antitumor activity of compounds based on 9-isothiocyanatoacridine.
- Vladimir Frecer, Cancer Research Institute SAS, Bratislava, Slovakia: Computer-assisted combinatorial design of bioactive compounds.
posters
21:30
DAY3
Treatment and Signaling Pathways
9:00 Section II.- Jan Sedlak, Cancer Research Institute SAS, Bratislava, Slovakia: Exploiting ITC-modulated signaling pathways in cancer therapy.
- Peter Ferenc, Institute of Biology and Ecology, Faculty of Science, UPJS, Kosice, Slovakia: Down-regulation of BCL-2 and AKT induced by combination of photoactivated hypericin and genistein in human breast cancer cells.
- Jozef Duraj, Cancer Research Institute SAS, Bratislava, Slovakia: Modulation of cisplatin resistance in human ovarian cancer cells by synthetic isothiocyanate E-4IB.
- Antonietta Melchini, University of Messina, Italy: Selective antiproliferative activity in vitro of structurally related isothiocyanates, erucin and sulforaphane, on human prostate cells.
- Eva Horvathova, Laboratory of Mutagenesis and Carcinogenesis, Cancer Research Institute SAS, Bratislava, Slovakia: Protective effects of carvacrol and rosemary oil supplementation on oxidative DNA damage induced in primary rat hepatocytes by 2,3-dimethoxy-1,4-naphthoquinone (DMNQ).
- Veronika Sackova, Institute of Biology and Ecology, Faculty of Science, UPJS, Kosice, Slovakia: Manumycin A as agent sensitizing adenocarcinoma cell to photodynamic treatment.
- Peter Solar, Institute of Biology and Ecology, Faculty of Science, UPJS, Kosice, Slovakia: HSP90 protein as a target for improving photodynamic therapy.
- Jaromir Mikes, Institute of Biology and Ecology, Faculty of Science, UPJS, Kosice, Slovakia: The role of protein P53 in photodynamic therapy with hypericin.
- Martin Kello, Institute of Biology and Ecology, Faculty of Science, UPJS, Kosice, Slovakia: Potentiation of photodynamic therapy with hypericin by exogenous polyunsaturated fatty acids.
Closing Remarks
12:00---------------------------------------------------------------------------
Schedule
| 10:00 | Walking City Tour through Old Town of Bratislava departing from Hotel Carlton - Hviezdoslavovo nám. 3, 811 02 Bratislava (2 hours tour); Map |
| 12:00 | Bus transfer to conference venue (Smolenice Castle) departing from hotel Carlton - Hviezdoslavovo nám. 3, 811 02 Bratislava |
| 12:20 | Bus transfer to Smolenice Castle stops at Main Train Station of Bratislava - Predstaničné námestie 1, 811 01 Bratislava; Map |
| 12:40 | Bus transfer to Smolenice Castle stops at Main Bus Station Mlynské Nivy - Mlynské Nivy 31, 821 09 Bratislava; Map |
| 13:00 | Bus transfer to Smolenice Castle stops at Bratislava International Airport - Letisko M. R. Štefánika, 823 11 Bratislava 22; Map |
| 14:00 | Arrival to Smolenice Castle Lunch |
| 14:00 - 16:00 | Registration, check in |
| 16:00 - 17:30 | Opening remarks ITC research in Slovakia |
| 17:30 - 18:00 | Coffee break |
| 18:00 - 19:30 | Section V |
| from 20:00 | Welcome Party (Smolenice Castle) |
| 8:00 | Breakfast |
| 9:00 - 10:45 | Section I. |
| 10:45 - 11:15 | Coffee break |
| 11:15 - 12:45 | Section III. |
| 13:00 | Lunch |
| 14:00 - 15:30 | Section IV. |
| 15:45 | Departure of sightseeing trip to Červený Kameň Castle (Red Stone Castle) |
| 16:30 | Visit of the Červený Kameň Castle |
| 18:00 | Departing from Červený Kameň Castle to Fugger Manor in Častá Village |
| 18:30 | Wine tasting in vine cellars of Fugger Manor |
| 19:00 | Farewell dinner in vine cellars of Fugger Manor House |
| 21:00 | Departure to Smolenice Castle |
| 21:30 | Poster session |
| 8:00 | Breakfast, check out |
| 9:00 - 10:00 | Section II. |
| 10:00 - 10:30 | Coffee break |
| 10:30 - 12:00 | Section II. cont. |
| 12:00 | Closing Remarks |
| 13:00 | Lunch |
| 14:00 | Bus transfer departure from Smolenice Castle to Bratislava |
| 15:00 | Bus - stops at International Airport of Bratislava |
| 15:30 | Bus - stops at Main Bus Station of Bratislava Mlynské Nivy |
| 15:50 | Bus - ends at Main Train Station of Bratislava |
© 2009 Cancer Research Institute